Transforming Growth Factor, beta 1 (TGFB1) (AA279-390), (active) (Active) protein (5µg)

Application

Functional Studies (Func), SDS-PAGE (SDS)CharacteristicsThe recombinant human/rhesus/canine TGFβ1 consists of 112 amino acids and has a calculated molecular mass of 12.8 kDa. it migrates as an approximately 13 & 26 kDa band in reduced and non-reduced SDS-PAGE respectively, corresponding to the monomer and homodimer.

Protein Structure:

A DNA sequence encoding the active form of human/rhesus/canine TGFβ1 (NP_000651.3) (Ala 279-Ser 390) was expressed and purified. Human, Rhesus and Canine TGFβ1 sequences are identical.
Predicted N-Term: Ala 279

Purity> 95 % as determined by HPLC.

Endotoxin Level< 1.0 EU per μg of the protein as determined by the LAL method

Biological Activity Comment Measured by its ability to inhibit cell proliferation of Mv-1-lu mink lung epithelial cells.
The ED₅₀ for this effect is typically 0.04-0.2 ng/mL